Congenital anomalies per 100,000 inhabitants in 2004.

     no data      less than 160      160-240      240-320      320-400      400-480      480-560      560-640      640-720      720-800      800-900      900-950      more than 950

Charles II of Spain was born mentally and physically disabled, probably caused by inbreeding in the House of Habsburg

A birth defect (or congenital disorder) is a defect in a baby at birth, or which develops in the first month of life. It is neutral as to whether the cause is genetic (inherited birth defect) or environmental (causes in the environment, that is, outside the foetus).