Founder could mean:

• Entrepreneur, in the sense of one who founds (starts) a company
• Laminitis, a horse illness in which "foundering" is a common symptom
• Founder Group, China's second-largest personal computer vendor
• Founder effect, a biological idea used to explain genetics in a small isolated population

Founders could mean:

• Founding Fathers, often called the "Founders", people who are important in starting an institution
• Founding Fathers of the United States, the political leaders who participated in the American Revolution as leaders of the Patriots
• Founders, a race of beings in the fictional Star Trek universe