Drone can mean:

In nature:

• Drone (bee), a male bee
• A male wasp
• A male ant

In vehicles:

• A unmanned aerial vehicle, often used for target practice or surveillance
• A remotely operated vehicle (ROV), used for mine clearing or underwater exploration
• An unmanned ground vehicle (UGV), a robotic land vehicle often used to replace humans in hazardous situations

In fiction:

• Drone (2017 film)
• A member of the Drones Club in P. G. Wodehouse's novels
• A humanoid that has been assimilated by the Borg in the fictional Star Trek universe
• "Drone" (Voyager episode), an episode of Star Trek: Voyager
• Drone Weapon, similar to a guided missile, in the Stargate universe
• Three robotic helpers in the movie Silent Running, named Huey, Dewey and Louie
• In the novel The Traveller, the term drones describes a class of citizens that have become exhausted
• Detective Drone, the hero of Victorian crime stories
• A Zerg worker unit in Starcraft

In music:

• Drone (music), a continuous note or chord
• The part of various musical instruments (such as the bagpipe) that produce the drone sound
• A bumbass, a folk instrument sometimes called a drone
• Drone music, a music style or genre related to background music and ambient music
• Drone Records, a record label
• "Drones," a song by Rise Against
• The Drones, a rock group from Melbourne, Australia